Formulation and in vitro evaluation of Eudragit S-100 coated naproxen matrix tablets for colon-targeted drug delivery system
The purpose of the present investigation was to prepare matrix tablets of naproxen using a hydrophobic polymer, i.e., Eudragit RLPO, RSPO, and combination of both, by wet granulation method.The tablets were further coated with different concentrations of Eudragit S-100, a pH-sensitive polymer, by dip immerse method.In vitro drug release studies of